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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BLM
All Species:
14.55
Human Site:
T581
Identified Species:
24.62
UniProt:
P54132
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54132
NP_000048.1
1417
159000
T581
L
A
A
S
K
S
S
T
A
A
Y
Q
P
I
K
Chimpanzee
Pan troglodytes
XP_510594
1417
158822
T581
L
A
A
S
K
S
S
T
A
A
Y
Q
P
I
K
Rhesus Macaque
Macaca mulatta
XP_001097543
1416
158885
T580
L
A
A
S
K
S
S
T
A
A
Y
Q
P
I
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88700
1416
158347
T589
F
P
A
S
K
S
S
T
A
T
Y
P
P
I
K
Rat
Rattus norvegicus
Q6AYJ1
621
69624
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515695
791
89186
Chicken
Gallus gallus
Q9I920
1142
126164
K351
G
P
H
P
T
A
P
K
S
G
C
G
I
S
V
Frog
Xenopus laevis
Q9DEY9
1364
152305
V541
D
S
P
A
A
P
S
V
S
S
K
N
V
P
Q
Zebra Danio
Brachydanio rerio
XP_701357
1261
139417
G470
I
A
S
V
M
S
V
G
D
E
S
V
F
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGI8
1487
166060
E652
L
D
D
D
G
F
P
E
Y
D
E
A
M
F
E
Honey Bee
Apis mellifera
XP_396209
961
109321
P170
K
P
I
M
S
S
V
P
I
T
K
D
K
L
E
Nematode Worm
Caenorhab. elegans
O18017
988
110641
A197
Q
K
S
D
S
E
I
A
L
N
Q
Q
R
H
D
Sea Urchin
Strong. purpuratus
XP_001175892
1394
152920
S581
R
S
S
G
P
A
S
S
F
Q
F
K
T
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35187
1447
163819
L593
Q
V
A
D
I
Q
E
L
D
N
D
L
K
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.1
N.A.
N.A.
76.9
21.2
N.A.
46.3
47.9
50.8
41.6
N.A.
27.8
30.9
26.5
31.5
Protein Similarity:
100
99.2
97.7
N.A.
N.A.
85.2
30.9
N.A.
50.1
60.7
66.6
54
N.A.
47
47.1
40.2
47.6
P-Site Identity:
100
100
100
N.A.
N.A.
73.3
0
N.A.
0
0
6.6
13.3
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
73.3
0
N.A.
0
13.3
40
26.6
N.A.
13.3
20
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
29
36
8
8
15
0
8
29
22
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
8
8
22
0
0
0
0
15
8
8
8
0
0
15
% D
% Glu:
0
0
0
0
0
8
8
8
0
8
8
0
0
8
15
% E
% Phe:
8
0
0
0
0
8
0
0
8
0
8
0
8
8
0
% F
% Gly:
8
0
0
8
8
0
0
8
0
8
0
8
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
8
0
8
0
8
0
8
0
0
0
8
36
8
% I
% Lys:
8
8
0
0
29
0
0
8
0
0
15
8
15
0
29
% K
% Leu:
29
0
0
0
0
0
0
8
8
0
0
8
0
8
0
% L
% Met:
0
0
0
8
8
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
15
0
8
0
0
0
% N
% Pro:
0
22
8
8
8
8
15
8
0
0
0
8
29
15
0
% P
% Gln:
15
0
0
0
0
8
0
0
0
8
8
29
0
0
8
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
15
22
29
15
43
43
8
15
8
8
0
0
8
8
% S
% Thr:
0
0
0
0
8
0
0
29
0
15
0
0
8
0
0
% T
% Val:
0
8
0
8
0
0
15
8
0
0
0
8
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
29
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _